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BPC-157 vs TB-500

Q: What is the difference between BPC-157 and TB-500?

BPC-157 is a Healing / Repair compound (Subcutaneous route) - Synthetic pentadecapeptide derived from human gastric juice protein. Studied for tissue repair. TB-500 is a Healing / Repair compound (Subcutaneous route) - Synthetic fragment of thymosin beta-4. Studied for soft-tissue and connective-tissue recovery.

Q: Which has a longer half-life, BPC-157 or TB-500?

TB-500 has the longest published plasma half-life (6 h), compared with BPC-157 (4 h).

Q: How often is each compound dosed in the research literature?

BPC-157: once daily at a published dose range of 0.25–0.5 mg; TB-500: once weekly at a published dose range of 2–10 mg. These are descriptive reference parameters, not dosing recommendations.

Q: Can you buy BPC-157 and TB-500 for research use?

Yes - BPC-157, TB-500 are available from New-U Research Compounds as lab-verified (>99% HPLC) compounds.

Published pharmacokinetic and receptor-characteristic comparison with primary-source references.

Updated August 2026 Research use only

BPC-157

Healing / Repair

TB-500

Healing / Repair

Key research differences

BPC-157 TB-500 Receptor profile Healing / Repair Healing / Repair Development status Research peptide Research peptide Published half-life 4 h 6 h Research distinction Synthetic pentadecapeptide derived from human gastric juice protein. Studied for tissue repair Synthetic fragment of thymosin beta-4. Studied for soft-tissue and connective-tissue recovery

Published research parameters

BPC-157 Body Protection Compound 157 View BPC-157 → TB-500 Thymosin Beta-4 fragment View TB-500 → Receptor profile Healing / Repair Healing / Repair Class Healing / Repair Healing / Repair Plasma half-life 4 h 6 h Time to Cmax 1 h 2 h Development status Research peptide Research peptide Study context Educational estimate Educational estimate Primary publications Sikiric P et al., Curr Pharm Des 16:1224 (peripheral t½ short, local effects prolonged) (2010) Goldstein AL et al., Ann N Y Acad Sci 1269:1 (2012) Summary Synthetic pentadecapeptide derived from human gastric juice protein. Studied for tissue repair. Synthetic fragment of thymosin beta-4. Studied for soft-tissue and connective-tissue recovery.

View published study parameters

BPC-157 Body Protection Compound 157 View BPC-157 → TB-500 Thymosin Beta-4 fragment View TB-500 → Route in published studies Subcutaneous Subcutaneous Published study interval Once daily Once weekly Published dose range 0.25–0.5 mg 2–10 mg Published study regimen No published study ladder No published study ladder

Source references

Sikiric P et al.

2010

Sikiric P et al., Curr Pharm Des 16:1224 (peripheral t½ short, local effects prolonged) (2010)

Chang CH et al.

2011

Chang CH et al., J Appl Physiol 110:774 (2011)

Goldstein AL et al.

2012

Goldstein AL et al., Ann N Y Acad Sci 1269:1 (2012)

Crockford D et al.

2010

Crockford D et al., Ann N Y Acad Sci 1194:179 (2010)

Frequently asked questions

What is the difference between BPC-157 and TB-500?

Which has a longer half-life, BPC-157 or TB-500?

How often is each compound dosed in the research literature?

Can you buy BPC-157 and TB-500 for research use?

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Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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