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CJC-1295 (with DAC) vs Sermorelin

Q: What is the difference between CJC-1295 (with DAC) and Sermorelin?

CJC-1295 (with DAC) is a Growth Hormone Secretagogue compound (Subcutaneous route) - GHRH analog with Drug Affinity Complex — albumin binding extends half-life to ~1 week. Sermorelin is a Growth Hormone Secretagogue compound (Subcutaneous route) - Recombinant GHRH 1-29. Published protocols typically schedule administration at bedtime to align with the natural overnight GH pulse.

Q: Which has a longer half-life, CJC-1295 (with DAC) or Sermorelin?

CJC-1295 (with DAC) has the longest published plasma half-life (~7.0 days (168 h)), compared with Sermorelin (~12 min).

Q: How often is each compound dosed in the research literature?

CJC-1295 (with DAC): once weekly at a published dose range of 1–2 mg; Sermorelin: once daily at a published dose range of 0.1–0.5 mg. These are descriptive reference parameters, not dosing recommendations.

Q: Can you buy CJC-1295 (with DAC) and Sermorelin for research use?

Yes - CJC-1295 (with DAC), Sermorelin are available from New-U Research Compounds as lab-verified (>99% HPLC) compounds.

Published pharmacokinetic and receptor-characteristic comparison with primary-source references.

Updated August 2026 Research use only

CJC-1295 (WITH DAC)

CJC-1295 (with DAC)

Growth Hormone Secretagogue

SERMORELIN

Sermorelin

Growth Hormone Secretagogue

Key research differences

CJC-1295 (with DAC) Sermorelin Receptor profile Growth Hormone Secretagogue Growth Hormone Secretagogue Development status Research peptide Research peptide Published half-life ~7.0 days (168 h) ~12 min Research distinction GHRH analog with Drug Affinity Complex — albumin binding extends half-life to ~1 week Recombinant GHRH 1-29. Published protocols typically schedule administration at bedtime to align with the natural overnight GH pulse

Published research parameters

CJC-1295 (with DAC) CJC-1295, DAC:GRF View CJC-1295 (with DAC) → Sermorelin GHRH 1-29 View Sermorelin → Receptor profile Growth Hormone Secretagogue Growth Hormone Secretagogue Class Growth Hormone Secretagogue Growth Hormone Secretagogue Plasma half-life ~7.0 days (168 h) ~12 min Time to Cmax 12 h ~6 min Development status Research peptide Research peptide Study context Peer-reviewed human PK Peer-reviewed human PK Primary publications Teichman SL et al., J Clin Endocrinol Metab 91:799 (half-life 5.8–8.1 d) (2006) Walker RF, Clin Interv Aging 1:307 (2006) Summary GHRH analog with Drug Affinity Complex — albumin binding extends half-life to ~1 week. Recombinant GHRH 1-29. Published protocols typically schedule administration at bedtime to align with the natural overnight GH pulse.

View published study parameters

CJC-1295 (with DAC) CJC-1295, DAC:GRF View CJC-1295 (with DAC) → Sermorelin GHRH 1-29 View Sermorelin → Route in published studies Subcutaneous Subcutaneous Published study interval Once weekly Once daily Published dose range 1–2 mg 0.1–0.5 mg Published study regimen No published study ladder No published study ladder

Source references

Teichman SL et al.

2006

Teichman SL et al., J Clin Endocrinol Metab 91:799 (half-life 5.8–8.1 d) (2006)

Walker RF

2006

Walker RF, Clin Interv Aging 1:307 (2006)

Frequently asked questions

What is the difference between CJC-1295 (with DAC) and Sermorelin?

Which has a longer half-life, CJC-1295 (with DAC) or Sermorelin?

How often is each compound dosed in the research literature?

Can you buy CJC-1295 (with DAC) and Sermorelin for research use?

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Research peptides at >99% HPLC-verified purity, third-party tested by Janoshik Analytical & Freedom Diagnostics, with Certificates of Analysis published per released batch. Supplied strictly for laboratory research use.

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