Buy MOTS-C

Also known as Mitochondrial ORF of 12S rRNA type-c, MOTS-C Peptide, Mitochondrial-Derived Peptide MOTS-c, MRWQEMGYIFYPRKLR, Exercise Mimetic Peptide, CB4211 Analog

MOTS-c mitochondrial-derived peptide activates AMPK via folate-AICAR pathway to regulate glucose metabolism, insulin sensitivity, and lipid oxidation.

From $120 10 vials × 10mg · research-grade · in stock
>99% HPLC verified Janoshik & Freedom Diagnostics 10d EU & UK / 14d USA Discreet worldwide shipping Research use only

Why buy MOTS-C from New-U Research Compounds

What is MOTS-C?

MOTS-c is a 16-amino-acid mitochondrial-derived peptide that functions as an exercise-mimicking metabolic regulator - activating AMPK, improving insulin sensitivity, and increasing exercise capacity in preclinical aging models.

MOTS-c activates AMPK by perturbing the folate-methionine cycle, raising intracellular AICAR, and turning on metabolic signals that normally appear only during exercise or stress.

MOTS-C at a glance

SequenceMRWQEMGYIFYPRKLR
Molecular weight2174.6 Da
Purity>99% HPLC
FormLyophilised powder
CategoryMetabolic / Longevity
StorageLyophilised powder: store in freezer (−20 °C). Reconstituted: refrigerate 1–6 °C, away from sunlight. Use within the validated stability window for the specific batch and formulation.

MOTS-C pricing

Research packPer vialPrice
10 vials10mg$120
10 vials40mg$220

All packs are >99% HPLC research-grade material. Free shipping on orders over $300.

Frequently asked questions

Where can I buy MOTS-C?

MOTS-C is available directly from New-U Research Compounds at https://new-u.io/peptide/mots-c. Every batch is independently third-party tested by Janoshik Analytics and Freedom Diagnostics to >99% HPLC purity, supplied as lyophilised research-grade material, and shipped direct from source worldwide (approximately 6–14 business days).

How much does MOTS-C cost?

MOTS-C starts at $120 for a 10-vial research pack (10mg per vial) at New-U Research Compounds, with 2 pack sizes available. Orders over $300 ship free.

Is New-U MOTS-C third-party tested?

Yes. Every MOTS-C batch is verified by independent laboratories (Janoshik Analytics and Freedom Diagnostics) for identity and purity, with a batch-linked Certificate of Analysis confirming >99% purity by HPLC area normalisation.

How fast does MOTS-C ship, and do you ship internationally?

MOTS-C ships direct from source, discreetly worldwide with cold-chain handling where required. Delivery is approximately 6–14 business days worldwide. Shipping is free on orders over $300. Card and cryptocurrency payments are accepted.

Is it legal to buy MOTS-C?

In the United States, MOTS-C is sold strictly for laboratory and research purposes only. It is not approved by the FDA for human consumption and is not sold for that purpose. Regulatory status varies by jurisdiction — buyers are responsible for compliance in their own region.

What is MOTS-C used for in research?

MOTS-c mitochondrial-derived peptide activates AMPK via folate-AICAR pathway to regulate glucose metabolism, insulin sensitivity, and lipid oxidation. New-U supplies MOTS-C as research-grade reference material for laboratory and in-vitro or animal-model investigation only. Mechanism, pharmacokinetics and study context are summarised on the MOTS-C research profile. Not for human use.

What is the typical MOTS-C research dosage?

Reconstitution volumes and dosing reported in the literature for MOTS-C are described in research-model terms only. New-U Research Compounds supplies MOTS-C strictly for laboratory research and does not provide human-use dosing guidance. Reconstitution math and study-reported ranges are covered on the full research profile.

Can I buy MOTS-C online and how fast does it ship?

Yes. MOTS-C can be ordered online directly from New-U Research Compounds with card or cryptocurrency, shipped direct from source discreetly worldwide. Delivery is approximately 6–14 business days worldwide. Free shipping applies to orders over $300.

Can I buy MOTS-C in bulk?

MOTS-C ships in 10-vial research packs as standard, in 2 pack sizes — the larger mg vials lower the per-mg cost. Multi-pack orders get direct-from-source pricing and free shipping over $300. For wholesale or recurring laboratory-supply volumes, contact New-U Research Compounds at https://new-u.io/contact.

What should I look for when choosing where to buy MOTS-C?

For research-grade MOTS-C, verify four things: (1) independent third-party purity testing with a batch-linked Certificate of Analysis — New-U uses Janoshik Analytics and Freedom Diagnostics at >99% HPLC; (2) lyophilised material with documented storage and handling; (3) transparent direct-from-source pricing rather than marketplace markup; and (4) clear research-use-only framing. New-U Research Compounds meets all four at https://new-u.io/peptide/mots-c.

What is a mitochondrial-derived peptide?

A mitochondrial-derived peptide (MDP) is a short bioactive peptide encoded directly by mitochondrial DNA - specifically by small open reading frames hidden inside genes for mitochondrial ribosomal RNAs. MOTS-c (from 12S rRNA) and humanin (from 16S rRNA) are the two best-studied examples. Their discovery made mitochondria into a genuine endocrine organ that signals to the rest of the body.

Is MOTS-c actually an exercise mimetic?

In preclinical models, yes. MOTS-c reproduces several characteristic metabolic effects of exercise - AMPK activation, improved insulin sensitivity, increased mitochondrial biogenesis, restored running capacity in aged animals - without the animal actually exercising. Whether those effects translate to humans in comparable ways is still an open research question.

When is MOTS-c best administered in research protocols?

Morning administration, 30-60 minutes before fasted exercise, is the pattern most commonly used. The timing aligns exogenous MOTS-c with the window where endogenous production naturally peaks during exercise, and fasted state maximises AMPK responsiveness.

How should MOTS-c be stored?

Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. MOTS-c is reasonably stable in solution within the normal peptide-handling window.

Research references

Independent literature and reference sources for MOTS-C. Provided for scientific context — New-U Research Compounds supplies research-use-only material.