Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) that activates telomerase, the enzyme responsible for maintaining telomere length. Developed by Professor Vladimir Khavinson, it has over 40 years of research demonstrating lifespan extension in multiple species.

How often should Epitalon be cycled?

The traditional Khavinson protocol uses 10–20 day courses repeated twice per year. Some researchers use quarterly cycles for ongoing telomere maintenance.

Does Epitalon affect sleep?

Yes. Epitalon restores melatonin production from the pineal gland, which often improves sleep quality and circadian rhythm regulation in research subjects.

Is Epitalon the same as Epithalon?

Yes. Epitalon and Epithalon are different transliterations of the same compound. The original Russian name Epithalamin refers to the natural pineal extract; Epitalon is the synthetic tetrapeptide derived from it.

Can Epitalon be combined with other longevity peptides?

Yes. Epitalon is commonly stacked with GHK-Cu for collagen and tissue repair, FOXO4-DRI for senolytic effects, or 5-amino-1MQ for metabolic support in longevity-focused research protocols.

Is "Epitalon" the same as "Epithalon"?

Yes - the two spellings refer to the same tetrapeptide (Ala-Glu-Asp-Gly). "Epitalon" and "Epithalon" are interchangeable transliterations of the Russian name. You will also see "Epithalone" and "AEDG peptide" in the literature, all referring to the same compound.

Does Epitalon actually extend lifespan in humans?

That is a longevity research question that has not been definitively answered. The cell culture telomere-elongation data is clear, and there are animal studies showing increased maximum lifespan. Human longevity data is limited to small studies and anecdotal reports. It remains a research compound, not a validated longevity therapy.

What is a typical research cycle?

The most commonly used protocol is 5-10 mg subcutaneous injection once daily for 10-20 consecutive days, followed by a 4-6 month rest period before the next cycle. This pulse-then-rest pattern mirrors the original Russian animal study protocols and is designed to avoid receptor desensitisation.

How should Epitalon be stored?

Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The tetrapeptide is small and simple, so it tolerates standard peptide handling well within the normal usage window.

Lyophilised · batch-documented · discreet packaging

>99% Purity // Janoshik Verified // Pineal Tetrapeptide // Telomerase Activator

Epitalon

Name: Epitalon
Brand: New-U Research Peptides
SKU: epitalon
Availability: InStock

Ala-Glu-Asp-Gly // CAS 307297-39-8 // Synthetic Epithalamin Tetrapeptide

The longevity peptide. 40+ years of research into telomerase activation and cellular ageing reversal.

Epitalon (also known as Epithalon or Epithalamin) is a synthetic tetrapeptide developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. Based on the natural polypeptide Epithalamin extracted from the pineal gland, Epitalon activates telomerase - the enzyme responsible for maintaining telomere length, one of the primary biomarkers of cellular ageing. Research spanning four decades demonstrates extended lifespan in multiple species, restored melatonin secretion, normalised circadian rhythms, and potent antioxidant effects.

40+ Years Research history

Up to 25% Lifespan extension (animal)

4 Amino acids

2×/Year Traditional cycle frequency

Third-party tested

Every batch independently verified by Janoshik & Freedom Diagnostics for purity and identity.

Full COA included

Certificate of Analysis confirms peptide purity, amino acid composition, and absence of contaminants.

Discreet shipping

Every order ships in plain, unmarked packaging with full tracking. No external branding or product details visible.

Research-grade

Uniform vial presentation, consistent labeling, and batch-level documentation every time.

10-vial pack

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Certificate of analysis per batch
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Research use only. All compounds are sold strictly for in-vitro research and educational purposes. Not approved for human use, therapeutic application, or as food or cosmetic products. By purchasing, you agree to use these products only for legitimate research purposes.

Epitalon

Third-party tested

Full COA included

Discreet shipping

Research-grade

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