How is Selank different from benzodiazepines?

Unlike benzodiazepines, Selank modulates GABA-A receptors without causing sedation, cognitive impairment, tolerance, or physical dependence. It produces anxiolytic effects while preserving - and even enhancing - cognitive function.

Can Selank be stacked with Semax?

Yes. Selank + Semax is a well-documented nootropic combination. Selank provides anxiolytic GABA modulation while Semax enhances BDNF and focus via melanocortin pathways. Together they offer complementary cognitive enhancement.

Is Selank clinically approved?

Selank has been approved in Russia as a prescription anxiolytic and nootropic nasal spray. It is not FDA-approved in the United States. Research-grade Selank is sold for in-vitro research purposes only.

How does Selank compare with benzodiazepines?

Russian clinical trials compared Selank directly with medazepam and found comparable anxiolytic efficacy. The key differences are the side effect profiles - Selank does not produce sedation, amnesia, dependence, or withdrawal, which are all common with benzodiazepines. It also adds neurotrophic BDNF support that benzodiazepines lack.

Is Selank a GABAA direct agonist?

No - it is an allosteric modulator rather than a direct agonist. It alters the affinity of the GABAA receptor for endogenous ligands (including GABA itself and endogenous benzodiazepine-like compounds) rather than binding the receptor as an agonist directly. That mechanistic difference is part of why it avoids the classic benzodiazepine side effect profile.

How does Selank compare with Semax?

Both are Russian heptapeptides with Pro-Gly-Pro stabilising tails and intranasal delivery, and they share several effects like BDNF elevation and monoamine modulation. Selank emphasises anxiolysis and mood stabilisation; Semax emphasises cognition and neuroprotection. They are often used together in research protocols covering both dimensions.

How should Selank be stored?

Keep the lyophilised powder frozen at −20 °C. After reconstitution with bacteriostatic water, refrigerate at 1-6 °C and protect from light. The Pro-Gly-Pro tail gives Selank much better stability than parent tuftsin (which has a half-life measured in seconds), but standard peptide handling still applies.

Lyophilised · batch-documented · discreet packaging

>99% Purity // Janoshik Verified // Tuftsin Analogue // Anxiolytic Nootropic

Selank

Name: Selank
Brand: New-U Research Peptides
SKU: selank
Availability: InStock

Synthetic Heptapeptide // Tuftsin Analogue // CAS 129954-34-3 // TP-7

Anxiolytic nootropic without sedation. GABA-A modulation meets cognitive enhancement.

Selank is a synthetic analogue of the endogenous immunopeptide tuftsin, developed at the Russian Institute of Molecular Genetics. It modulates GABA-A receptors, increases serotonin and dopamine levels, and upregulates BDNF. Unlike benzodiazepines, Selank produces anxiolytic effects without sedation, tolerance, or withdrawal - while simultaneously improving memory encoding and retrieval. Also studied for immune modulation via the tuftsin receptor pathway.

GABA-A Primary target

No Tolerance vs Benzodiazepines

751.86 Molecular weight

2–4 Weeks Cycle length

Third-party tested

Every batch independently verified by Janoshik & Freedom Diagnostics for purity and identity.

Full COA included

Certificate of Analysis confirms peptide purity, amino acid composition, and absence of contaminants.

Discreet shipping

Every order ships in plain, unmarked packaging with full tracking. No external branding or product details visible.

Research-grade

Uniform vial presentation, consistent labeling, and batch-level documentation every time.

10-vial pack

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Janoshik & Freedom Diagnostics verified
Certificate of analysis per batch
Direct-from-manufacturer sourcing
Discreet, unmarked packaging

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Research use only. All compounds are sold strictly for in-vitro research and educational purposes. Not approved for human use, therapeutic application, or as food or cosmetic products. By purchasing, you agree to use these products only for legitimate research purposes.

Selank

Third-party tested

Full COA included

Discreet shipping

Research-grade

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