TB-500 is a synthetic peptide based on the active region of Thymosin Beta-4. It promotes systemic tissue repair, cell migration, and angiogenesis, working at distant sites from injection.

How is TB-500 different from BPC-157?

TB-500 provides systemic healing through actin regulation and angiogenesis, while BPC-157 focuses on local tissue repair through growth factor modulation. They complement each other in stacked protocols.

What is the loading phase?

TB-500 protocols typically use a loading phase of 2–2.5 mg twice weekly for 4–6 weeks, followed by a maintenance phase of 2–2.5 mg once weekly.

Can TB-500 help with flexibility?

Research suggests TB-500 reduces scar tissue and adhesions, which may improve flexibility and range of motion in damaged tissue.

What is the difference between TB-500 and Thymosin Beta-4?

Thymosin Beta-4 is the full 43-amino-acid protein found naturally in most human cells. TB-500 is a synthetic seven-amino-acid fragment (Ac-LKKTETQ) that preserves the actin-binding domain responsible for most of the parent protein's wound-healing activity. The shorter peptide is much cheaper to synthesise and is widely used as a research surrogate.

How does TB-500 compare with BPC-157?

Both are research peptides in the healing category but they act through different mechanisms. BPC-157 primarily drives VEGFR2/eNOS and FAK signalling, while TB-500 works through actin regulation and NF-κB modulation. Many preclinical protocols combine them to exploit the distinct pathways.

Is TB-500 approved for human use?

No. TB-500 is an investigational research peptide and is not approved for human therapeutic use by any major regulator. It is also on the World Anti-Doping Agency (WADA) prohibited list for competing athletes. Material is supplied strictly for laboratory research.

How should TB-500 research material be stored?

Store the lyophilised powder frozen and protected from light. Once placed into solution under laboratory conditions, keep it cold (1–6 °C) and protected from light, and follow the batch-specific handling documentation. Peptide material degrades slowly under cold, dark storage.

What vial sizes does New-U offer for TB-500, and how is it reconstituted?

New-U supplies TB-500 in 10-vial research packs at 2 mg, 5 mg, and 10 mg per vial, with the larger vials lowering the per-mg cost. For laboratory preparation, lyophilised TB-500 is dissolved in bacteriostatic water: concentration in mg/mL equals the vial mass in mg divided by the millilitres of diluent added (e.g. a 5 mg vial in 2.5 mL gives 2 mg/mL). All material is research-use-only; no human-use dosing instructions are provided.

What is the molecular weight and half-life of TB-500?

The TB-500 fragment (Ac-LKKTETQ, formula C₃₇H₆₆N₁₀O₁₄) has a molecular weight of 889.02 Da, far smaller than the 4921 Da full-length 43-amino-acid Thymosin Beta-4 it derives from. Rodent pharmacokinetics report a subcutaneous elimination half-life of roughly 1.5-3 hours, with peak plasma concentration (Cmax 200-400 ng/mL) reached 0.5-1 hour after dosing.

Why do researchers run the BPC-157 + TB-500 stack?

TB-500 and BPC-157 are studied together because they support tissue repair through different mechanisms: TB-500 through G-actin regulation, angiogenesis, and NF-κB modulation, and BPC-157 through the VEGFR2/eNOS pathway and growth-hormone-receptor upregulation. New-U Research Compounds supplies both as separate research-grade vials for laboratories investigating the combination. This is a research observation, not a human-use protocol.

Is TB-500 banned in sport?

Yes. TB-500 (and Thymosin Beta-4-related peptides) are on the World Anti-Doping Agency (WADA) prohibited list at all times. New-U supplies TB-500 strictly for in-vitro and preclinical laboratory research, not for human use, veterinary use, or athletic performance enhancement.

Lyophilised · batch-documented · discreet packaging

Research peptide

TB-500

Name: TB-500
Brand: New-U Research Peptides
SKU: tb-500
Availability: InStock

Thymosin Beta-4 Fragment - Cell Migration & Tissue Repair Peptide

TB-500 is a synthetic peptide based on the active region (Ac-LKKTETQ) of Thymosin Beta-4, a 43-amino acid protein found in virtually all human and animal cells. It acts as a major G-actin sequestering peptide, regulating cytoskeletal dynamics and enabling rapid cell migration to injury sites. This systemic mobility distinguishes TB-500 from locally acting repair peptides.

>99% (HPLC) HPLC purity

4963.50 Da mol. weight

Lyophilised Powder Presentation

EU·US·UK Ship regions

Third-party tested

Every batch independently verified by Janoshik & Freedom Diagnostics for purity and identity.

Full COA included

Certificate of Analysis confirms peptide purity, amino acid composition, and absence of contaminants.

Discreet shipping

Every order ships in plain, unmarked packaging with full tracking. No external branding or product details visible.

Research-grade

Uniform vial presentation, consistent labeling, and batch-level documentation every time.

10-vial pack

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Janoshik & Freedom Diagnostics verified
Certificate of analysis per batch
Direct-from-manufacturer sourcing
Discreet, unmarked packaging

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Research use only. All compounds are sold strictly for in-vitro research and educational purposes. Not approved for human use, therapeutic application, or as food or cosmetic products. By purchasing, you agree to use these products only for legitimate research purposes.

TB-500

Third-party tested

Full COA included

Discreet shipping

Research-grade

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